Keytruda: Uses, Warnings, Dosage, Side Effects & More

Keytruda uses explained – Learn about Keytruda cost, warnings, dosage, side effects, company details, price in India, and its role in treating cancer.
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What is Keytruda?

Keytruda, scientifically known as pembrolizumab, is an immunotherapy drug. Unlike chemotherapy, which directly kills cancer cells, Keytruda boosts the immune system so that the body can fight cancer naturally.

  • Drug Class: PD-1 (programmed death receptor-1) inhibitor
  • Route: Intravenous injection
  • First Approved: 2014 by the U.S. FDA

According to Keytruda’s official website, this medicine is now approved in more than 85 countries.

Keytruda Company & Development

Keytruda is developed and marketed by Merck & Co., Inc., a global pharmaceutical leader. Merck is known for producing innovative cancer treatments and investing heavily in research.

  • Brand Name: Keytruda
  • Generic Name: Pembrolizumab
  • Manufacturer: Merck & Co. (MSD outside the USA)

What Types of Cancer Does Keytruda Treat?

One of the biggest questions is: What kind of cancer does Keytruda treat? Currently, it is approved for multiple cancers, including:

Lung Cancer

Keytruda is commonly prescribed for non-small cell lung cancer (NSCLC), often in combination with chemotherapy.

Melanoma

It has shown great results in treating advanced melanoma, a deadly form of skin cancer.

Head and Neck Cancer

Doctors use Keytruda to treat recurrent or metastatic head and neck squamous cell carcinoma.

Other Approved Cancers

  • Hodgkin’s lymphoma
  • Cervical cancer
  • Bladder cancer
  • Liver cancer
  • Stomach cancer
  • Kidney cancer

How Keytruda Works in the Body?

Our immune system has “checkpoints” to prevent it from attacking healthy cells. Cancer cells exploit these checkpoints to hide.

Keytruda blocks the PD-1 pathway, which allows immune cells (T-cells) to recognize and kill cancer cells effectively.

Keytruda Uses in Cancer Treatment

Doctors recommend Keytruda for:

  • First-line cancer treatment
  • Cases where chemotherapy failed
  • Preventing cancer recurrence
  • Boosting survival rates in advanced cancer

Keytruda Dosage and Administration

Standard Dosage Forms

  • Given through IV infusion every 3 to 6 weeks
  • Common dosage: 200 mg every 3 weeks or 400 mg every 6 weeks

How Doctors Decide Dosage

The dose depends on:

  • Type of cancer
  • Patient’s weight and health
  • Previous treatments

Keytruda Side Effects

Common Side Effects

  • Fatigue
  • Fever
  • Loss of appetite
  • Nausea
  • Cough

Serious Risks & Warnings

  • Lung inflammation
  • Liver damage
  • Kidney issues
  • Hormonal imbalances

If any severe side effects appear, doctors may pause or stop treatment.

Signs That Keytruda is Working

Patients and doctors can track Keytruda’s success by:

  • Shrinking of tumors in scans
  • Improved breathing and energy
  • Longer survival times
  • Blood test improvements

Keytruda Cost & Price Details

Keytruda Cost in India

The cost per vial in India ranges between ₹2,80,000 to ₹3,50,000, depending on the hospital and availability.

Keytruda Cost in Australia

In Australia, a dose can cost AUD $6,000 – $8,000, though government subsidies may reduce expenses.

Global Price Range

  • USA: $10,000 – $13,000 per month
  • Europe: €7,000 – €9,000 per month

Is Keytruda Expensive?

Yes, Keytruda is considered expensive worldwide. Its high price is due to research, manufacturing, and its role as a life-saving immunotherapy.

What is the Success Rate of Keytruda?

Success rates vary depending on cancer type:

  • Melanoma: up to 40% long-term survival
  • Lung Cancer: improves survival by 20–30% compared to chemo
  • Other cancers: depends on stage and patient health

Patient Experiences & Case Studies

Real patients often report:

  • Slower cancer progression
  • Better quality of life
  • Hope after failed chemo

Keytruda Warnings & Precautions

  • Not suitable for patients with severe autoimmune disorders
  • Should be used carefully during pregnancy
  • Requires regular liver, kidney, and thyroid function tests

Keytruda vs Other Cancer Treatments

Compared to chemotherapy:

  • Fewer side effects
  • Works with the immune system
  • More effective in certain cancers

However, it doesn’t work for everyone, which is why genetic testing is often done before starting therapy.

Future of Keytruda in Oncology

Researchers are testing Keytruda for:

  • Breast cancer
  • Colon cancer
  • Pancreatic cancer

The future looks promising, with clinical trials expanding rapidly.

FAQs

1. What kind of cancer does Keytruda treat?
Keytruda treats multiple cancers, including lung, melanoma, head and neck, bladder, liver, and stomach cancers.

2. Is Keytruda expensive?
Yes, it’s costly, with prices ranging from $6,000 to $13,000 per month depending on the country.

3. What is the success rate of Keytruda?
Success varies: about 40% survival for melanoma patients and 20–30% improvement for lung cancer.

4. How much does Keytruda cost in India?
In India, Keytruda costs between ₹2,80,000 to ₹3,50,000 per dose.

5. How much does Keytruda cost in Australia?
A dose costs around AUD $6,000 – $8,000, but government health schemes reduce costs.

6. What are the side effects of Keytruda?
Common effects include fatigue, fever, nausea, while serious risks involve lung, kidney, and liver issues.

Conclusion

As someone who has been researching and writing in the health sector for three years, I can confidently say that Keytruda is a revolutionary treatment in oncology. It offers hope for patients with difficult-to-treat cancers, though its high cost and side effects can be challenging.

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