What Is VIZZ?
VIZZ™ (aceclidine ophthalmic solution 1.44%) is the first FDA-approved eye drop for presbyopia, a common age-related condition causing blurry near vision.
How Does VIZZ Eye Drops Work?
✔ Mechanism: Aceclidine is a cholinergic muscarinic agonist that:
- Contracts the iris sphincter muscle → Creates a pinhole effect
- Extends depth of focus → Improves near vision without affecting distance vision
- Works in 30 minutes, lasts up to 10 hours
✔ Unlike other miotics, VIZZ minimizes ciliary muscle stimulation, reducing side effects like headaches.
Table of Contents
VIZZ Clinical Trial Results (CLARITY-1 & CLARITY-2)
| Study | VIZZ Success Rate | Control Group | Key Finding |
|---|---|---|---|
| CLARITY-1 (N=336) | 65% improved 3+ lines near vision | 12% (brimonidine) | P < 0.01 |
| CLARITY-2 (N=153) | 71% improved 3+ lines near vision | 8% (placebo) | P < 0.01 |
Key Benefits:
- Rapid improvement (30 minutes)
- Long-lasting (up to 10 hours)
- Once-daily dosing
VIZZ Eye Drops Side Effects & Safety
Most Common Side Effects
- Instillation site irritation (20%)
- Dim/dark vision (16%)
- Headache (13%)
- Conjunctival hyperemia (8%)
Who Should Avoid VIZZ?
❌ Allergy to aceclidine
❌ Severe dry eye or corneal disease
❌ Acute eye infections
VIZZ Eye Drops Availability & Pricing
- Samples for doctors: October 2025
- Full commercial launch: Mid-Q4 2025
- Expected cost: Not yet disclosed (likely similar to other specialty eye drops, ~$50-$100/month)
🔹 Prescription required? Yes (ophthalmologist or optometrist)
VIZZ vs. Other Presbyopia Treatments
| Treatment | How It Works | Pros | Cons |
|---|---|---|---|
| VIZZ Eye Drops | Pinhole effect via iris contraction | Non-invasive, fast-acting, lasts 10h | Temporary dim vision, mild irritation |
| Reading Glasses | Magnifies near objects | Cheap, no side effects | Inconvenient, doesn’t treat cause |
| Multifocal Contacts | Multiple vision zones | No surgery needed | Adaptation period, dry eye risk |
| LASIK (Monovision) | One eye near, one far | Permanent solution | Surgical risks, not reversible |
FAQs About VIZZ Eye Drops
1. How long does VIZZ take to work?
30 minutes, with peak effect at 3 hours.
2. Can I use VIZZ with contacts?
Yes, but remove lenses before application and wait 10 minutes before reinserting.
3. Is VIZZ better than reading glasses?
For active adults, VIZZ offers hands-free clarity without carrying glasses.
4. Will insurance cover VIZZ?
Likely yes (similar to other prescription eye drops).
5. Are there natural alternatives?
Bilberry extract & omega-3s may help, but no proven alternative matches VIZZ’s efficacy.
Key Takeaways
✅ First FDA-approved presbyopia eye drop
✅ Works in 30 mins, lasts 10 hours
✅ 65-71% success rate in clinical trials
✅ Mild side effects (dim vision, irritation)
✅ Launching Q4 2025
🚀 Stay tuned for updates at www.VIZZ.com
