What Is Vostally?
Vostally (ramipril oral solution) is a newly FDA-approved liquid form of the widely prescribed ACE inhibitor ramipril, designed specifically for adults who have difficulty swallowing pills.
✔ FDA-approved July 23, 2025
✔ First oral liquid ramipril for hypertension
✔ For adults who struggle with swallowing pills (dysphagia)
✔ Once-daily dosing
✔ Reduces risk of stroke, heart attack & cardiovascular death
✔ Expected launch late 2025
Table of Contents
What Is Vostally (Ramipril Oral Solution) Used For?
Vostally is an ACE inhibitor prescribed for:
✅ Hypertension (high blood pressure) – Lowers BP to prevent strokes & heart attacks
✅ High-risk cardiovascular patients (55+ years) – Reduces heart attack, stroke, or death risk
✅ Post-heart attack heart failure – Lowers hospitalization & death risk
Who Should NOT Take Vostally?
Vostally is contraindicated in patients with:
❌ History of angioedema (severe swelling)
❌ Allergy to ACE inhibitors
❌ Hereditary/idiopathic angioedema
❌ Taking sacubitril/valsartan (must wait 36 hours between doses)
❌ Diabetics on aliskiren (increases kidney risks)
How Does Vostally Work?
Vostally blocks angiotensin-converting enzyme (ACE), which:
➞ Relaxes blood vessels → lowers blood pressure
➞ Reduces strain on the heart → prevents heart failure
➞ Decreases risk of stroke & heart attack
Vostally vs. Traditional Ramipril Tablets
| Feature | Vostally (Oral Solution) | Standard Ramipril (Tablet) |
|---|---|---|
| Form | Liquid | Pill |
| Best For | Dysphagia patients | Patients who can swallow pills |
| Dosing | Once daily | Once daily |
| Absorption | Faster in some cases | Standard |
| Cost | Likely higher (TBD) | Generic options available |
How Vostally Protects Your Heart and Brain
1. Blood Pressure Control: The First Defense
- Relaxes blood vessels → lowers systolic/diastolic BP
- Reduces arterial damage that leads to:
- Strokes (ischemic and hemorrhagic)
- Heart attacks
- Kidney disease
2. Plaque Stabilization in Arteries
- Prevents rupture of vulnerable plaques (main cause of heart attacks)
- Slows progression of atherosclerosis (artery hardening)
3. Heart Remodeling Prevention
- Reduces left ventricular hypertrophy (dangerous heart thickening)
- Improves ejection fraction in heart failure patients
Who Benefits Most from Vostally?
Top Candidate Profiles:
- Elderly patients with swallowing difficulties
- Stroke survivors with dysphagia
- Heart failure patients needing precise dosing
- Hypertension patients who’ve struggled with pills
Dosing & Administration Advantage
- Liquid form allows:
- Easier titration for optimal dosing
- Better absorption in some GI conditions
- More precise dosing than split tablets
When Will Vostally Be Available?
- Expected late 2025
- Prescription-only
- Check RosemontPharmaceuticals.com for updates
FAQs About Vostally
1. Is Vostally better than regular ramipril?
It’s not “better” but an alternative for those who can’t swallow pills.
2. Can I switch from ramipril tablets to Vostally?
Yes, but consult your doctor first.
3. What’s the price of Vostally?
Pricing not yet announced, likely higher than generic ramipril.
4. Does Vostally have more side effects?
No, same risks as ramipril tablets (e.g., cough, dizziness, kidney effects).
5. Can children take Vostally?
No, FDA-approved only for adults.
Why This Approval Matters
- Helps elderly, stroke survivors & dysphagia patients
- Improves medication adherence (easier to take than pills)
- Expands treatment options for high-risk cardiovascular patients
💬 Industry Insight:
“Vostally removes a major barrier for patients who need ACE inhibitors but struggle with pills.”
– Jeff Bryant, President of Sabal Therapeutics (Rosemont)
